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Two-Thirds Of Women Undergoing IVF Have Live Birth By Sixth Attempt, Study Suggests.

January 5, 2016

My longstanding clinical impression is supported by this study.  I have said many times that persistence pays off.  While we don’t promote high cycle number on a regular basis, there is some benefit in many situations.  This study is from the UK, where pregnancy rates are lower to begin with at baseline.  You can see that the pregnancy rates go down with each subsequent cycle, especially after the 3rd cycle.  This is a natural statistical effect due to the “easier” problems being solved by pregnancy and those persons dropping out of the overall pool.  As we get to higher cycle numbers, the pool of patients is smaller and would naturally have a higher percentage of patients with more significant impediments to pregnancy.  There are patients that don’t have severe problems who have statistically not been successful, who could benefit from persisting and doing more cycles.

http://www.nytimes.com/2015/12/23/health/with-in-vitro-fertilization-persistence-pays-off-study-suggests.html?ref=health&_r=0

Michael D. Fox, MD
Jacksonville Center
Reproductive Medicine
jcrm.org 

   
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